Umphrey's McGee has played Handshake Drugs 1 time. It was first played on August 18, 2019 at Greenfield Lake Amphitheater, Wilmington, NC, and last on August 18, 2019 at Greenfield Lake Amphitheater, Wilmington, NC (527 shows since last played).
| Date | Venue |
|---|---|
| Aug 18, 2019 | Greenfield Lake Amphitheater, Wilmington, NC |
How many times have you heard Handshake Drugs?
Track your shows on MySetlists and see every song you've caught live.
Track your shows← All Umphrey's McGee song stats
Handshake Drugs on All Things Umphrey's: every performance, jam notes and more.
Setlist data from All Things Umphrey's: allthings.umphreys.com. Updated October 21, 2026.